Gene therapy clinical trials: what about the environment? A comparison between the Netherlands and North America
Gene therapy offers perspectives for the treatment of diseases that are difficult to cure, such as cancer and various genetic disorders. Experimental gene therapy studies have been conducted for over twenty years. The majority of these studies take place in North America. Although it is fairly clear which experiments take place, it is not always clear how the environmental risk assessment is performed.
This report presents an overview of gene therapy trials conducted in North America and describes how the risk assessment is performed. It also describes the application procedures. The data are compared to the situation in the Netherlands in order to learn from the different approaches.