Within the GMO regulations, microorganisms are classified into four pathogenicity classes. This classification is based on the properties of the microorganism and the extent to which it can cause disease in humans, animals or plants.
Class 1 comprises non-pathogenic (apathogenic) micro-organisms. Classes 2 to 4 comprise micro-organisms that are increasingly pathogenic, with class 4 micro-organisms often causing very serious, potentially fatal disease. Each pathogenicity class is linked to a containment level. Depending on the type of classified organism, these are included in Annex 2 (non-pathogenic organisms) or Annex 4 (pathogenic organisms) of the GMO Regulation.
Every year, COGEM publishes new overview lists of organisms it has classified (viruses, bacteria, fungi, parasites, single-celled and multicellular organisms). For plants, it also maintains an overview of the containment measures required for experiments with GM plant species. These overview lists are translated in English, and can be downloaded in the publications section.